trans-3-Aminocyclohexanecarbonitrile hydrochloride
trans-3-Aminocyclohexanecarbonitrile hydrochloride
CAS: 920966-30-9
Molecular Formula: C7H13ClN2
trans-3-Aminocyclohexanecarbonitrile hydrochloride - Names and Identifiers
| Name | trans-3-Aminocyclohexanecarbonitrile hydrochloride |
| Synonyms | trans-3-Aminocyclohexanecarbonitrile hydrochloride |
| CAS | 920966-30-9 |
trans-3-Aminocyclohexanecarbonitrile hydrochloride - Physico-chemical Properties
| Molecular Formula | C7H13ClN2 |
| Molar Mass | 160.64452 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD22548413 |
trans-3-Aminocyclohexanecarbonitrile hydrochloride - Risk and Safety
| Hazard Class | 6.1 |
trans-3-Aminocyclohexanecarbonitrile hydrochloride - Introduction
trans-3-Aminocyclohexanecarbonitrile hydrochloride is an organic compound, also known as a trans-3-Aminocyclohexanecarbonitrile hydrochloride. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C7H13ClN
-Molecular weight: 155.64g/mol
-Melting point: 141-144°C
-Solubility: Soluble in water and common organic solvents
Use:
- trans-3-Aminocyclohexanecarbonitrile hydrochloride has certain application in the field of medicine. It is commonly used in the synthesis of potential pharmaceutical compounds, such as chiral drugs and bioactive molecules.
-Due to its chiral structure, it can be used as an important intermediate in enantiomer separation and drug synthesis.
Preparation Method:
The preparation of trans-3-Aminocyclohexanecarbonitrile hydrochloride is usually completed by the following steps:
1. Under appropriate reaction conditions, cyclohexene reacts with nucleophile propylene carbamate to generate cyclohexenyl methanol.
2. Cyclohexenyl carbinol undergoes nitration reaction and reacts with hydrocyanic acid to generate cyclohexenyl carbonitrile.
3. Cyclohexenyl carbonitrile is reacted with an appropriate reducing agent to give (1R,3R)-3-aminocyclohexane-1-carbonitrile.
4. Finally, a trans-3-Aminocyclohexanecarbonitrile hydrochloride was obtained by reaction with hydrochloric acid.
Safety Information:
The safety assessment of trans-3-Aminocyclohexanecarbonitrile hydrochloride is limited, so the following items should be paid attention to when using it:
-It may be irritating to the eyes and skin, so direct contact should be avoided.
-During use, avoid inhalation or ingestion.
-Should operate in a well-ventilated place and wear appropriate personal protective equipment.
-Store away from heat sources and flammable substances.
It is strongly recommended to carefully read the relevant safety data sheet (SDS) and follow the correct operating instructions before using this compound. If necessary, please consult professional advice.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C7H13ClN
-Molecular weight: 155.64g/mol
-Melting point: 141-144°C
-Solubility: Soluble in water and common organic solvents
Use:
- trans-3-Aminocyclohexanecarbonitrile hydrochloride has certain application in the field of medicine. It is commonly used in the synthesis of potential pharmaceutical compounds, such as chiral drugs and bioactive molecules.
-Due to its chiral structure, it can be used as an important intermediate in enantiomer separation and drug synthesis.
Preparation Method:
The preparation of trans-3-Aminocyclohexanecarbonitrile hydrochloride is usually completed by the following steps:
1. Under appropriate reaction conditions, cyclohexene reacts with nucleophile propylene carbamate to generate cyclohexenyl methanol.
2. Cyclohexenyl carbinol undergoes nitration reaction and reacts with hydrocyanic acid to generate cyclohexenyl carbonitrile.
3. Cyclohexenyl carbonitrile is reacted with an appropriate reducing agent to give (1R,3R)-3-aminocyclohexane-1-carbonitrile.
4. Finally, a trans-3-Aminocyclohexanecarbonitrile hydrochloride was obtained by reaction with hydrochloric acid.
Safety Information:
The safety assessment of trans-3-Aminocyclohexanecarbonitrile hydrochloride is limited, so the following items should be paid attention to when using it:
-It may be irritating to the eyes and skin, so direct contact should be avoided.
-During use, avoid inhalation or ingestion.
-Should operate in a well-ventilated place and wear appropriate personal protective equipment.
-Store away from heat sources and flammable substances.
It is strongly recommended to carefully read the relevant safety data sheet (SDS) and follow the correct operating instructions before using this compound. If necessary, please consult professional advice.
Last Update：2024-04-09 21:00:56
